Edwardsiella tarda Hfq: impact on host infection and global protein expression
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چکیده
منابع مشابه
Edwardsiella tarda Hfq: impact on host infection and global protein expression
Hfq is an RNA-binding protein that plays an important role in many cellular processes. In this study, we examined the biological effect of the Hfq of Edwardsiella tarda, a severe fish pathogen with a broad host range that includes humans. To facilitate the study, a markerless hfq in-frame deletion wild type, TXhfq, was constructed. Compared to the wild type TX01, TXhfq exhibited (i) retarded pl...
متن کاملEdwardsiella tarda Eta1, an in vivo-induced antigen that is involved in host infection.
Edwardsiella tarda, a Gram-negative bacterium, is a severe fish pathogen that can also infect humans. In this study, we identified, via in vivo-induced antigen technology, an E. tarda antigen, Eta1, and analyzed its function in a Japanese flounder (Paralichthys olivaceus) model. Eta1 is composed of 226 residues and shares homology with putative bacterial adhesins. Quantitative real-time reverse...
متن کاملEdwardsiella tarda Eta 1 : an in vivo - induced antigen that is 1 involved in host infection
11 12 13 *To whom correspondence should be addressed 14 15 Mailing address: 16 Institute of Oceanology 17 Chinese Academy of Sciences 18 7 Nanhai Road 19 Qingdao 266071, China 20 Phone: 86-532-82898829 21 Fax: 86-532-82898829 22 Email: [email protected] 23 24 25 26 Running title: An E. tarda antigen involved in host infection 27 Copyright © 2012, American Society for Microbiology. All Rights Rese...
متن کاملIntramacrophage Infection Reinforces the Virulence of Edwardsiella tarda.
UNLABELLED Edwardsiella tarda is an important pathogenic bacterium that can replicate in macrophages. However, how the intramacrophage infection process affects the virulence of this bacterium is essentially unknown. Here, we show that E. tarda replicates and induces a caspase-1-dependent cell pyroptosis in a murine macrophage model. Via pyroptosis, intracellular E. tarda escapes to the extrace...
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The ability of Edwardsiella tarda to hemolyse red blood cells was investigated. Most E. tarda strains (> 80%) produced a hemolysin when assayed by either an agar overlay or contact-dependent hemolysis technique. This activity was cell-associated (CAH) and not released into the culture supernatant under routine conditions. When quantified, E. tarda strains significantly produced 30-40-fold highe...
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ژورنال
عنوان ژورنال: Veterinary Research
سال: 2014
ISSN: 1297-9716
DOI: 10.1186/1297-9716-45-23